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Methylprednisolone is indicated to treat any condition in which rapid and intense corticosteroid effect is required such as: Dermatological disease: severe erythema multiforme (Stevens-Johnson syndrome).
Allergic states: bronchial asthma, severe seasonal and perennial allergic rhinitis, angioneurotic edema, anaphylaxis.
Gastrointestinal disease: ulcerative colitis, Crohn's disease.
Respiratory disease: aspiration of gastric contents, fulminating or disseminated tuberculosis (with appropriate anti-tuberculous chemotherapy).
Neurological disorders: cerebral oedema secondary to cerebral tumour acute exacerbations of multiple sclerosis superimposed on a relapsing-remitting background.
Miscellaneous: T.B. meningitis (with appropriate antituberculous chemotherapy) transplantation.
